High strength porous PLA gyroid scaffolds manufactured via fused deposition modeling for tissue-engineering applications

نویسندگان

چکیده

Gyroid polylactic acid (PLA) scaffolds with different unit cell sizes of 2 ​mm (G2), 2.5 (G25), and 3 (G3) were fabricated via fused deposition modeling for bone tissue engineering applications. The porosity the PLA ranged from 86% to 90%. structural anisotropy value was 3.80, 2.00, 1.04 G2, G25, G3, respectively. Compressive test results indicated that both dense porous showed elastic-plastic deformation behavior in building transverse directions. compressive elastic modulus yield strength 118–180 ​MPa 2–8 direction 106–138 2.5–6.0 direction, tensile 51–63 1.5–4.5 11–17 1–5 gyroid significantly higher values (up three times) compared other structures reported literature. can be anticipated as promising scaffold biomaterials applications by virtue their bone-mimicking structure good mechanical properties.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

In-vitro evaluation of Polylactic acid (PLA) manufactured by fused deposition modeling

BACKGROUND With additive manufacturing (AM) individual and biocompatible implants can be generated by using suitable materials. The aim of this study was to investigate the biological effects of polylactic acid (PLA) manufactured by Fused Deposition Modeling (FDM) on osteoblasts in vitro according to European Norm / International Organization for Standardization 10,993-5. METHOD Human osteobl...

متن کامل

Biomaterials as Porous Scaffolds for Tissue Engineering Applications: a Review

In tissue engineering, biomaterials play a critical role, act as a 3D template, provide mechanical support, and give artificial extracellular matrix environment (ECM) for neo-tissue formation. Only one type of biomaterials is not enough for both hard and soft tissue engineering. That’s why all types of biomaterials i.e. metals, ceramics, & polymers have their own importance in making tissue eng...

متن کامل

Modeling of Multifunctional Deformable Porous Scaffolds for Soft Tissue Engineering

Porous membranes/scaffolds such as guided tissue regeneration (GTR) membranes, cell sheets, tissue matrices or polymeric meshes are being widely used in soft tissue engineering to regenerate damaged, diseased tissue or wound. These membranes are mostly regular porous structures with repeating internal architecture. When they are applied onto wound area, various forces caused by bandage, contrac...

متن کامل

A novel three-dimensional printing of electroconductive scaffolds for bone cancer therapy application

Objective(s): Tissue engineering aims to achieve a tissue, which has highly interconnected porous microstructure concurrent with appropriate mechanical and biological properties. Materials and Methods: Therefore, the microstructure scaffolds are of great importance in this field. In the present study, an electroconductive poly-lactic acid (EC-PLA) filament used to fabricate a porous bone ...

متن کامل

Polycaprolactone Scaffolds Fabricated via Bioextrusion for Tissue Engineering Applications

The most promising approach in Tissue Engineering involves the seeding of porous, biocompatible/biodegradable scaffolds, with donor cells to promote tissue regeneration. Additive biomanufacturing processes are increasingly recognized as ideal techniques to produce 3D structures with optimal pore size and spatial distribution, providing an adequate mechanical support for tissue regeneration whil...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Smart materials in medicine

سال: 2021

ISSN: ['2590-1834']

DOI: https://doi.org/10.1016/j.smaim.2020.10.003